Debajani Deka

Debajani Deka

Gauhati Medical College and Hospital, India

Title: Gastrointestinal stromal tumour- a review literature

Abstract

Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract and originate from the interstitial cells of Cajal. They arise most commonly from the stomach or small intestine, with a median age of 60 years. We did not find any relationship between GIST and ABO blood group and Rh factor. Mutations in KIT exon 11 are found to be more common in larger tumors, and the presence of this mutation has been shown to have an adverse prognostic influence. Deletions compared with point mutations in exon 11 have also been found to be a significant unfavorable factor in patients with gastric GISTs. The study group includes all cases of GIST and extra-GIST. Review literatures were taken from Internet Google search and some websites of high index journals. The data extruded mainly were sites of the gastrointestinal tract, histological types, different immunohistochemical markers, etc., Stomach is the most common site of GIST around 70%. Spindle cell is the most common histological variety; CD117 is frequently found immunohistochemical finding. From the abovementioned results, we can easily come to the diagnosis of specific type of GIST and its respective therapeutic measures.

Biography

Debajani Deka completed a basic course in biomedical research(naptel). Yale school of medicine ( anatomy of chest,neck,abdomen and pelvis). John Hopkins University ( neuroscience and neuroimaging). Gauhati Medical College. Her Education - Assam Medical College & Hospital, Dibrugarh, MBBS, Silchar Medical College & Hospital, Silchar; MD, Jr Resident Doctor, LGB Regional Inst of Mental Health; NRHM-Medical Officer, Assam Medical College & Hospital in All India Inst of Medical Sciences, Bhopal, All India Inst of Medical Sciences, Jodhpur; GNRC Hospital(North Guwahati) as Emergency Medicine Senior Resident Doctor. Guwahati Medical College & Hospital, Guwahati; Asst. Prof Anatomy, GIMSH, W Bengal; Member: Scholars Academic and Scientific Society, SOCA; Anatomical Society of India, International Association of Oncology. She attended many national and international conferences/workshops AIIMS Raipur, AIIMS Jodhpur, Jipmer, AIIMS Bilaspur, USA (San Francisco, Chicago), Dubai UAE, Germany, UK Bershire (Best e-poster presentation), SGTeAnatConf2023, Scientex Conference Dubai, UAE. 2023 etc.; Her publications—3 Book chapters; and 15 research papers published in national and international journals with 441 reads & 198 mentions.; Awards ISSN Research Bibhusan Award, Youngest Best Researcher Award, Dr. Sarvapalli Radhakrishnan Best Faculty Award, Dr. A.P.J Abdul Kalam Lifetime Achievement Award, Rashtriya Gaurav Top 30 Icon Award, Rifacimento international award for best biography of the year. Worlds Surgeons & Neurocare Webinar Award (USA)(San Francisco, 2021, Chicago 2022)VD Good Award, East Asian Best Teacher Award.