Vaddatti Tejeswini

Vaddatti Tejeswini

NRI Medical College, India

Title: Effectuation of International Academy of Cytology Yokahama reporting system of breast cytology to assess malignancy risk and accuracy


IntroductionRecently the International Academy of Cytology (IAC) proposed a new Yokahama reporting system for breast fine needle aspiration cytology (2019) in order to standardise reporting pattern and to link Cytology reporting to management algorithms. 

Aims and Objectives: To categorize the samples according to the newly proposed IAC Yokahama reporting system of breast cytology and to assess diagnostic accuracy & corresponding risk of malignancy (ROM) for each category. 

Materials and methodsThis is a retrospective study of breast cytology cases done at the department of Pathology. The slides are retrieved from pathology archives and classified using a recently proposed IAC, Yokahama reporting system of breast cytology into five categories. The risk of malignancy, sensitivity, specificity and diagnostic accuracy were estimated on the basis of final histopathological diagnosis. 

Results: Of the 386 cases breast FNAC, 226 (55.55%) had corresponding histological diagnosis. The respective ROM for each category was 22.22% for category 1 (insufficient material), 5.32% for category 2 (benign), 26.31% for category 3 (atypical), 100% for category 4 (suspicious for malignancy), and category 5 (malignant). When only malignant cases were considered positive tests, the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 89.66%, 100%, 100%, 90.2% and 94.69% respectively.

ConclusionsThe present study showed statistically significant sensitivity, specificity and diagnostic accuracy, especially with malignant cases. Hence, using IAC Yokahama reporting system of breast cytology is effective to standardise the reporting in various institutes and provide clear guidelines to clinician for further management.


Will be updated soon.