Maxillary osteosarcoma is a rare malignant bone tumor arising from the craniofacial skeleton and represents a small fraction of head and neck sarcomas. Compared with long bone osteosarcoma, craniofacial osteosarcomas are uncommon and often present with nonspecific symptoms, which can delay diagnosis. Orbital involvement from a maxillary osteosarcoma is particularly rare and may result in serious ocular complications. Early recognition and timely multidisciplinary management are important for improving outcomes. We report a case of a 41 year old male who presented with progressive nasal obstruction for one month and loss of vision in the left eye for 20 days. Clinical examination revealed a cystic mass in the left nasal cavity, a proliferative lesion involving the hard palate, and significant proptosis of the left eye with complete loss of vision. Imaging demonstrated a destructive mass arising from the left maxillary sinus with erosion of the orbital floor and compression of the optic nerve. Initial biopsy suggested a chondro osseous respiratory epithelial hamartoma. However, due to the aggressive behavior of the lesion and irreversible vision loss, definitive surgical management was planned. The patient underwent left total maxillectomy with orbital exenteration along with elective tracheostomy. Histopathological examination confirmed conventional osteosarcoma grade 3 which is poorly differentiated and high grade. Following surgery, the patient received adjuvant chemotherapy with cisplatin and doxorubicin. At six month follow up, the patient remained clinically stable with no evidence of local recurrence or distant metastasis. Orbital extension of maxillary osteosarcoma is rare and aggressive. Comprehensive imaging, histopathological confirmation, and radical surgical resection combined with chemotherapy are essential for disease control. Multidisciplinary collaboration between ophthalmology, otorhinolaryngology, oncology, and pathology teams plays a key role in successful management of such complex cases.

Sannareddy Pavan Krishna Reddy is a final year postgraduate resident in the department of ophthalmology at Sri Ramachandra Medical College and Research Institute in Chennai, India. He is actively involved in clinical ophthalmology, patient care, and academic research with particular interests in cornea and ocular surface disorders, neuro ophthalmology, and orbital diseases. During his postgraduate training, he has participated in several academic conferences and scientific meetings. He has presented research papers and e-posters at conferences organized by the Tamil Nadu Ophthalmic Association. His presentations include Papilledema in Cerebral Venous Thrombosis with Hyperhomocysteinemia and Polycythemia, Case of Orbital Necrotizing Fasciitis, and Tear Film Stability and Eye Cosmetics Understanding Dry Eye Disease in Women. He has also presented work titled Analyzing dry eye disease frequently asked questions using artificial intelligence for enhancing awareness and comprehension at Chen Eye Con. He has contributed to academic publications and case reports focusing on clinically significant and rare ophthalmic conditions. He continues to engage in research, conference presentations, and collaborative learning with the aim of improving understanding of complex ophthalmic diseases and promoting evidence based ophthalmic practice.